IEEE Open Journal of Engineering in Medicine and Biology
Articles
Untargeted Large Volume Hyperthermia Reduces Tumor Drug Uptake From Thermosensitive Liposomes
Krishna K. Ramajayam, A. Marissa Wolfe, Anjan Motamarry, Georges J. Nahhas, John Yost, Michael J. Yost, Dieter Haemmerich
Goal: The impact of hyperthermia (HT) method on tumor drug uptake with thermosensitive liposomes (TSL) is not well understood. Methods: We created realistic three-dimensional (3-D) computer models that simulate TSL-encapsulated doxorubicin (TSL-DOX) delivery in mouse tumors with three HT methods...
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Posted on 28 SEP 2021