IEEE Transactions on Biomedical Engineering

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Guide-wired Helical Microrobot for Percutaneous Revascularization in Chronic Total Occlusion in-vivo Validation
Here we show an enhanced powered guide wired helical millirobot for mechanical thrombectomy in cardiovascular intervention capable of autonomous therapeutics. We build up and demonstrate a millimeter robot fabrication with a spherical joint and a guidewire, a high-power and frequency actuation via external electromagnetic field control, and autonomous therapeutic motions comprise driving, steering, and drilling. We validate all performances in two-dimensional fluidic channels mimicking the vascular network and finally in-vivo environments. Beyond nature-inspired millirobot technologies, our work has the potential of advanced mechanical thrombectomy application and advancement of micrometer and millimeter robot technology toward real clinical utilization... Read more