IEEE Transactions on Biomedical Engineering

Featured Articles
Direct electrical stimulation of the human brain has inverse effects on the theta and gamma neural activities
Lech et. al studied the electrophysiological response to direct electrical stimulation (DES) systematically applied in human patients at a wide range of parameters, with particular focus on the neural activities associated with memory and cognition. Subjects were stimulated in blocks of alternating frequency and amplitude parameters during quiet wakefulness. Amplification of the theta (4–7 Hz) and attenuation of the gamma (29–52 Hz) power-in-band was observed with increasing the stimulation parameters. These findings reveal the utility of simple power-in-band features for understanding and optimizing the effects of electrical stimulation on brain activities and functions... Read more
Special Issue: BRAIN
A Million-Plus Neuron Model of the Hippocampal Dentate Gyrus: Critical Role for Topography in Determining Spatio-Temporal Network Dynamics
Phillip J. Hendrickson, Gene J. Yu, Dong Song, and Theodore W. Berger, University of Southern California, USA Developing large-scale, quantitatively based models of neural systems has become a realizable goal in recent years, largely because of three major developments: (i) the accumulation... Read more