IEEE Transactions on Biomedical Engineering

The radical sympathectomy and percutaneous catheter-based renal denervation (RDN) are two techniques proposed to treat life-threatening resistant hypertension. However, sympathectomy has been abandoned due to the procedure being too invasive, and RDN resulted in variation in blood pressure reduction between patients due to suboptimal denervation. Thus, a method to effectively ablate renal nerves while not being very invasive is needed to treat the resistant hypertension patients. Here we propose a minimally invasive Laparoscopic Denervation System (LDS) to serve this unmet clinical need. The LDS employs a direct renal nerve ablation technique while not imparting thermal arterial damage... Read more

Hamid Ladjal, Jean-Luc Hanus, Antoine Ferreira Volume: 60, Issue: 9, Page: 2461-2471 Cell manipulation is a prevalent process in the field of molecular biology. This process plays an important role in intracytoplasmic sperm injection (ICSI), pronuclei deoxyribonucleic acid (DNA) injection, therapeutic and regenerative... Read more