IEEE Transactions on Biomedical Engineering

Test Article
Direct electrical stimulation of the human brain has inverse effects on the theta and gamma neural activities
Lech et. al studied the electrophysiological response to direct electrical stimulation (DES) systematically applied in human patients at a wide range of parameters, with particular focus on the neural activities associated with memory and cognition. Subjects were stimulated in blocks of alternating frequency and amplitude parameters during quiet wakefulness. Amplification of the theta (4–7 Hz) and attenuation of the gamma (29–52 Hz) power-in-band was observed with increasing the stimulation parameters. These findings reveal the utility of simple power-in-band features for understanding and optimizing the effects of electrical stimulation on brain activities and functions... Read more