Transactions on NanoBioscience

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Principles of Information Storage in Small-Molecule Mixtures
Molecular data systems have the potential to store information at dramatically higher density than existing electronic media. Some of the first experimental demonstrations of this idea have used DNA, but nature also uses a wide diversity of smaller non-polymeric molecules... Read more
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Bacterial Relay for Energy-Efficient Molecular Communications
In multi-cellular organisms, molecular signaling spans multiple distance scales and is essential to tissue structure and functionality. Molecular communications is increasingly researched and developed as a key subsystem in the Internet-of-Nano-Things paradigm. While short range microscopic diffusion communications is well... Read more
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Implementing Nonlinear Feedback Controllers Using DNA Strand Displacement Reactions
We show how an important class of nonlinear feedback controllers can be designed using idealized abstract chemical reactions and implemented via DNA strand displacement (DSD) reactions. Exploiting chemical reaction networks (CRNs) as a programming language for the design of complex... Read more
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Identification of DNA-Binding Proteins by Combining Auto-Cross Covariance Transformation and Ensemble Learning
DNA-binding proteins play a pivotal role in various intra- and extra-cellular activities ranging from DNA replication to gene expression control. With the rapid development of next generation of sequencing technique, the number of protein sequences is unprecedentedly increasing. Thus it... Read more
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Packet Fragmentation and Reassembly in Molecular Communication
This paper describes packet fragmentation and reassembly to achieve reliable molecular communication among bionanomachines. In the molecular communication described in this paper, a sender bionanomachine performs packet fragmentation, dividing a large molecular message into smaller pieces and embedding into smaller... Read more
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A Graphene and Aptamer Based Liquid Gated FET-Like Electrochemical Biosensor to Detect Adenosine Triphosphate
Here we report successful demonstration of a FET-like electrochemical nano-biosensor to accurately detect ultralow concentrations of adenosine triphosphate. As a 2D material, graphene is a promising candidate due to its large surface area, biocompatibility and demonstrated surface binding chemistries and... Read more
Articles, Published Articles
Rapid, Affordable, and Point-of-Care Water Monitoring Via a Microfluidic DNA Sensor and a Mobile Interface for Global Health
Contaminated water is a serious concern in many developing countries with severe health consequences particularly for children. Current methods for monitoring waterborne pathogens are often time consuming, expensive, and labor intensive, making them not suitable for these regions. Electrochemical detection... Read more