IEEE Transactions on Biomedical Engineering

Featured Articles
Contrast-free detection of focused ultrasound-induced blood-brain barrier opening using diffusion tensor imaging
Karakatsani et al. report a contrast-free method to detect focused ultrasound (FUS)-induced blood-brain barrier (BBB) opening using diffusion tensor imaging (DTI). The localized BBB opening was hypothesized to result to a transient change in the diffusion pattern of water molecules and was tested in a non-human primate model, which closely resembled the human anatomy. They found that fractional anisotropy within the targeted area increased by 82% after the procedure, showing that DTI can confirm BBB opening without the use of contrast agents, increasing the safety of the methodology since contrast does not have to cross into the brain parenchyma... Read more
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Topological Properties of the Structural Brain Network in Autism via ε-neighbor Method
When a structural brain network is constructed by the existing parcellation methods such as the automated anatomical labeling (AAL), the topological properties of the network change depending on the scale of parcellation and arbitrary connectivity matrix thresholding. To overcome these... Read more
TBME 60th Anniversary
A Brief History of Tissue Models for Cardiac Electrophysiology
Craig S. Henriquez, Duke University, Volume 61, Issue 5, Page:1457-1465 The first biophysically based cardiac tissue model, combining equations for the cell-to-cell connections with a realistic representation of the membrane current fluxes, was developed nearly 45 years ago. In the decades that... Read more
Featured Articles
Feature-Preserving Smoothing of Diffusion Weighted Images Using Nonstationarity Adaptive Filtering
Yan-Li Zhang, Wan-Yu Liu, Isabelle E. Magnin, and Yue-Min Zhu Volume: 60, Issue: 6, Page: 1693-1701 Investigating the microstructure of tissues is essential for understanding the cause of their diseases, which is in turn beneficial to the diagnosis and the treatment in... Read more