IEEE Transactions on Biomedical Engineering

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Computer Assisted Planning for Curved Laser Interstitial Thermal Therapy
We present a detailed retrospective study on clinical epilepsy patient data, showing the potential advantage of following a curved path in the brain for both insertion and ablation purposes. Curved trajectories that follow the contours of given anatomy, as the amygdala-hippocampal complex (AHC) in the case of refractory epilepsy, were associated with a statistically significant improvement compared to their straight counterpart. Benefits were measured in terms of several quantitative metrics including percentage coverage of the ablation region and a published risk score to quantify, among other aspects, the safe distance between the ablation trajectory and critical brain regions... Read more