IEEE Open Journal of Engineering in Medicine and Biology

Systemic sclerosis (SSc) is a rare autoimmune, systemic disease with prominent fibrosis of skin and internal organs. Early diagnosis of the disease is crucial for designing effective therapy and management plans. Machine learning algorithms, especially deep learning, have been found... Read more

In recent years, driven by scientific and clinical concerns, there has been an increased interest in the analysis of functional brain networks. The goal of these analyses is to better understand how brain regions interact, how this depends upon experimental... Read more

In this work, silicon micromachined structures (SMS), consisting of arrays of 3-µm-thick silicon walls separated by 50-µm-deep, 5-µm-wide gaps, were applied to investigate the behaviour of eight tumour cell lines, with different origins and biological aggressiveness, in a three-dimensional (3D)... Read more