IEEE Transactions on Biomedical Engineering

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Patient-Specific Computational Simulations of Hyperpolarized 3He MRI Ventilation Defects in Healthy and Asthmatic Subjects
     Combined, medical imaging data and respiratory computer simulations may facilitate novel insight into pulmonary disease phenotypes, including the relationship between its structure and function. This integration may enable improved classification and treatment of severe asthma. Severe asthma (15% of asthmatics)... Read more
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Efficient Multiple Organ Localization in CT Image Using 3D Region Proposal Network
Organ localization is an essential preprocessing step for many medical image analysis tasks, such as image registration, organ segmentation, and lesion detection. In this paper, we propose an efficient method for multiple organ localization in CT image using a 3D... Read more
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DukeSim: A Realistic, Rapid, and Scanner-Specific Simulation Framework in Computed Tomography
The purpose of this study was to develop a CT simulation platform that is: 1) compatible with voxel-based computational phantoms; 2) capable of modeling the geometry and physics of commercial CT scanners; and 3) computationally efficient. Such a simulation platform... Read more
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A New Adaptive Gamma Correction Based Algorithm Using DWT-SVD for Non-Contrast CT Image Enhancement
The performances of medical image processing techniques, in particular CT scans, are usually affected by poor contrast quality introduced by some medical imaging devices. This suggests the use of contrast enhancement methods as a solution to adjust the intensity distribution... Read more
Articles, Published Articles
The Utility of Cloud Computing in Analyzing GPU-Accelerated Deformable Image Registration of CT and CBCT Images in Head and Neck Cancer Radiation Therapy
Abstract: The images generated during radiation oncology treatments provide a valuable resource to conduct analysis for personalized therapy, outcomes prediction, and treatment margin optimization. Deformable image registration (DIR) is an essential tool in analyzing these images. We are enhancing and examining... Read more
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Optimal Procedure Planning and Guidance System for Peripheral Bronchoscopy
Jason D. Gibbs, Michael W. Graham, Rebecca Bascom, Duane C. Cornish, Rahul Khare, and William E. Higgins, Pennsylvania State University Volume: 61, Issue, 3, Page: 638-657 Summary: With the development of multi-detector computed tomography (MDCT) scanners and ultrathin bronchoscopes, the use of... Read more
Articles, Published Articles
Constrained TpV-minimization for Enhanced Exploitation of Gradient Sparsity: Application to CT Image Reconstruction
Exploiting sparsity in the image gradient magnitude has proved to be an effective means for reducing the sampling rate in the projection view angle in computed tomography (CT). Most of the image reconstruction algorithms developed for this purpose solve a... Read more
Articles, Published Articles
Detection of Cardiac Quiescence from B-Mode Echocardiography using a Correlation-Based Frame-to-Frame Deviation Measure
Two novel methods for detecting cardiac quiescent phases from B-mode echocardiography using a correlation-based frame-to-frame deviation measure were developed. Accurate knowledge of cardiac quiescence is crucial to the performance of many imaging modalities, including computed tomography coronary angiography (CTCA). Methods:... Read more