IEEE Transactions on Biomedical Engineering

Featured Articles
CMOS-compatible, Flexible, Intracortical Neural Probes
Flexible intracortical neural probes elicit a lower tissue response compared to rigid implants. However, silicon-based neural probes incorporating complementary metal-oxide-semiconductor (CMOS) circuitry offer improved scalability and functionality. We describe a novel neural implant combining short, needle-like CMOS-based probe tips with flexible polyimide cables. Ultra-thin shuttles enable their complete implantation into brain tissue. An optimized cable fabrication process based on ion beam and plasma etching increases line and pad density, thus minimizing the bond area between cable and probe tip to widths of 100 µm. The synergetic approach surpasses the limitations of each individual probe technology and should be considered in future developments... Read more
Featured Articles
Smart Cell Culture Monitoring and Drug Test Platform Using CMOS Capacitive Sensor Array
Integrated Microfluidic-Microelectronic Systems have recently received significant interest, as a new paradigm in the design and implementation of chemical/biological analysis platforms, for both clinical and research purposes. This paper presents a novel method for monitoring drug cytotoxicity using a hybrid... Read more