IEEE Transactions on Biomedical Engineering

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An Automated Microrobotic Platform for Rapid Detection of C. diff Toxins
Clostridium difficile (C. diff) infection is a serious public health threat, and early diagnosis of this toxin-mediated disease is important. This paper presents a fluorescence imaging-integrated microrobotic system and related methods for automated and rapid detection of C. diff toxins. The automated mobile detection process finishes within 20 minutes, and then qualitative and semi-quantitative results are immediately given. This process is at least 8 times shorter than that of the conventional ELISA. The proposed microrobotic platform offers an automated, rapid and low-cost C. diff toxin detection technique that has good competency for future clinical use... Read more