Transactions on NanoBioscience

Articles
Hierarchical micro-/nanotopography for tuning structures and mechanics of cells probed by atomic force microscopy
Extracellular matrix plays an important role in regulating the behaviors of cells, and utilizing matrix physics to control cell fate has been a promising way for cell and tissue engineering. However, the nanoscale situations taking place during the topography-regulated cell-matrix... Read more
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Atomic Force Microscopy in Characterizing Cell Mechanics for Biomedical Applications: A Review
Cell mechanics is a novel label-free biomarker for indicating cell states and pathological changes. The advent of atomic force microscopy (AFM) provides a powerful tool for quantifying the mechanical properties of single living cells in aqueous conditions. The wide use... Read more
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A Graphene and Aptamer Based Liquid Gated FET-Like Electrochemical Biosensor to Detect Adenosine Triphosphate
Here we report successful demonstration of a FET-like electrochemical nano-biosensor to accurately detect ultralow concentrations of adenosine triphosphate. As a 2D material, graphene is a promising candidate due to its large surface area, biocompatibility and demonstrated surface binding chemistries and... Read more
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Nanoscale Surface Characterization of Human Erythrocytes by Atomic Force Microscopy: A Critical Review
Erythrocytes (red blood cells, RBCs), the most common type of blood cells in humans are well known for their ability in transporting oxygen to the whole body through hemoglobin. Alterations in their membrane skeletal proteins modify shape and mechanical properties... Read more