IEEE Transactions on Biomedical Engineering

Pulse wave velocity (PWV) is a pressure-dependent marker of arterial stiffness, wherefore pulse arrival time (PAT) has been widely investigated for cuff-less blood pressure (BP) estimation. However, PAT is typically biased by a cardiac delay and peripheral vasculature. Therefore, we demonstrate an ultrasound-based method for central PAT segmentation into cardiac isovolumic contraction (IVC) and vascular pulse transit time (PTT). Contrasting peripheral PAT, central PTT-based PWV explained more than twice as much variability in the reference PWV and yielded significantly lower BP estimation errors. Thereby this unilateral arterial stiffness assessment bears the potential to improve cardiovascular risk assessment in clinical routines... Read more

Oscillometric devices are widely used for automatic cuff blood pressure (BP) measurement. These devices estimate BP from the oscillometric cuff pressure waveform using population average methods. Hence, the devices may only be accurate over a limited BP range. The objective... Read more

Vascular stiffness is an indicator of cardiovascular health, with carotid artery stiffness having established correlation to coronary heart disease and utility in cardiovascular diagnosis and screening. State of art equipment for stiffness evaluation are expensive, require expertise to operate and... Read more