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2021 IEEE Medal Winner Ruzena Bajcsy
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The COVID-19 Vaccine Landscape


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June 2021
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The RADxSM Tech Process: Accelerating Innovation for COVID-19 Testing
In the wake of the COVID-19 pandemic, the need for rapid and accurate diagnostic testing across populations quickly became evident. In response, the National Institutes of Health (NIH) was determined not only to invest heavily in this area but to change the process by which grant proposals were reviewed and funded in order to spur faster development of viable technologies. The Rapid Acceleration of Diagnostics (RADx) initiative was designed to speed innovation, commercialization, and implementation of potential COVID-19 diagnostic technology... Read more

CRISPR Tech Behind Super-Sensitive, Smartphone COVID Test
Advanced CRISPR technology is part of a new test that determines within minutes whether a person has been infected with even very low levels of the SARS-CoV-2 virus (the cause of COVID-19), and also quickly and directly measures the viral load, or how much replicating virus is in a person’s body [1]... Read more
New Advances in Transplants and Bioengineering Aid in Replacing the Womb
When Kayla Edwards turned 13, she began to wonder if she was different. It started as a seed of suspicion when her friends began their menstrual cycles, and hers never arrived. Her grandmother was late, she learned, but for Edwards, it still seemed odd. She had hit puberty’s other benchmarks—the hormones, the breasts—just no cycle... Read more
Researchers Seek Answers for Millions With Long COVID-19
“I am now eight-and-a-half months into my journey with long COVID … My symptoms include diagnosed post-COVID tachycardia and acute fatigue. I also have chest tightness and breathlessness from time to time; anxiety; muscle aches and pains, especially in the evening; memory loss; and insomnia.”—38-year-old female from the U.K... Read more
Filling a Cavity in Dental Care
About a decade ago, Dian Baker, a professor at Sacramento State School of Nursing, responded to a directive from the Centers for Disease Control (CDC) asking health care practitioners to do something about the thorny and serious problem of ventilator hospital-acquired pneumonia, which afflicts thousands of people each year. After consulting with colleagues on the issue, Baker noticed something interesting. Although hospital ventilators had been widely assumed to be the cause of this problem, the truth was that most people getting pneumonia in hospitals weren’t on ventilators. The true culprit may come as a surprise: Nurses were shirking the unpleasant task of brushing the teeth of seriously ill patients... Read more
New Apps Drive Health Care Innovation, Access to Care
With the ubiquitous nature of smartphones, apps are a regular part of our day-to-day lives. They are also becoming a larger presence in health care, where they have the ability to expand access to care, help people monitor health changes, provide support for people living with chronic conditions, and coordinate communication between patients and their doctors. From detecting skin cancer to helping people with diabetes, new apps aim to change how people think about their health... Read more

Journal Updates

IEEE Transactions on

Biomedical Engineering

MAY 2021
TBME, Volume 68, Issue 5, May 2021
Development and Characterization of a Non-Thermal Plasma Source for Therapeutic Treatments
A non−thermal plasma (NTP) system constituted by a radiofrequency generator directly coupled to a treatment probe is described. The NTP generated was analyzed and characterized to determine a plasma safety profile and a spreading technique to be used on heat−sensitive matter. When NTP interacts with surrounding air particles produces reactive oxygen and nitrogen species that exhibit bactericidal and antiseptic effects due to their strong biochemical reactivity. Afterward, the NTP source was validated through bacterial deactivation trials, biological tests and promoting and in vivo wound closure performed in mice. NTP source demonstrated faster wound healing than that performed with conventional treatments... Read more
Rapid impedance spectroscopy for monitoring tissue impedance, temperature, and treatment outcome during electroporation-based therapies
Electroporation-based therapies (EBT) employ high voltage pulsed electric fields to permeabilize tumor tissue; this results in a detectable impedance change. Impedance characterization with a potentiostat is limited by acquisition time (~10s) as this timeframe is larger than pulse periods used with EBTs (~1s). Here, we develop a rapid electrical impedance spectroscopy (EIS) method for impedance characterization (<1s) of electroporation and thermal effects during irreversible electroporation. A biphasic rectangular chirp signal allows for impedance measurements between 1.8 kHz – 4.93 MHz. For the first time, we show impedance analysis at high frequencies (~1 MHz) can delineate thermal effects from electroporation effects... Read more
IEEE Journal of

Biomedical And Health Informatics

MARCH 2021
The IEEE Journal of Biomedical And Health Informatics Volume 25, Issue 3 has been published.
Prediction of Alzheimer’s Disease Progression with Multi-Information Generative Adversarial Network
Alzheimer’s disease (AD) is a chronic neurodegenerative disease, and its long-term progression prediction is definitely important. The structural Magnetic Resonance Imaging (sMRI) can be used to characterize the cortical atrophy that is closely coupled with clinical symptoms in AD and... Read more